ANALYSIS OF REPEATED MEASURES DESIGNS WITH CHANGING COVARIATES IN CLINICAL-TRIALS
成果类型：
Article
署名作者：
PATEL, HI
刊物名称：
BIOMETRIKA
ISSN/ISSBN：
0006-3444
发表日期：
1986
页码：
707715
关键词：
摘要：
A multivariate model is proposed for analysing repeated measures designs with changing or within-subject covariates. Under the assumption of multivariate normality the likelihood ratio tests are derived for testing certain linear hypotheses. Some special designs are discussed and a numerical example is given to illustrate the method for analysing a two-period crossover design.