TESTS OF EFFECT IN 1-J MATCHED CASE-CONTROL STUDIES BASED ON A MODIFIED LIKELIHOOD APPROACH

成果类型:
Article
署名作者:
LANGHOLZ, B; THOMAS, D; CHEN, TJ; RHODES, P
署名单位:
Centers for Disease Control & Prevention - USA
刊物名称:
BIOMETRIKA
ISSN/ISSBN:
0006-3444
发表日期:
1990
页码:
897900
关键词:
摘要:
A test of an effect in matched case-control studies, natural in an analysis of variance context, compares within matched set case-control mean differences to the within matched set variances after removing the case-control effect. For large odds ratios, heuritis reasoning suggests that this new test should be more powerful than the standard score test when two or more controls are matched to any case. Asymptotic theory confirms this in some important situations. Simulation results reveal, however, that the differences in power at sample size relevant to epidemiological studies are small.