Marginal analyses of longitudinal data with an informative pattern of observations

• 成果类型: Article
• 署名作者: Farewell, D. M.
• 署名单位: Cardiff University
• 刊物名称: BIOMETRIKA
• ISSN/ISSBN: 0006-3444
• DOI: 10.1093/biomet/asp068
• 发表日期: 2010
• 页码: 6578
• 关键词: semiparametric regression; estimating equations; repeated outcomes; binary data; discrete; models; size

摘要

We consider solutions to generalized estimating equations with singular working correlation matrices, of which the estimator of Diggle et al. (2007) is a special case. We give explicit conditions for consistent estimation when the pattern of observations may be informative. In such cases, simulations reveal reduced bias and reduced mean squared error compared with existing alternatives. A study of peritoneal dialysis is used to illustrate the methodology.