Application of the logistic function to bio-assay
成果类型：
Article
署名作者：
Berkson, J
署名单位：
Mayo Clinic
刊物名称：
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
ISSN/ISSBN：
0162-1459
DOI：
10.2307/2280041
发表日期：
1944
页码：
357-365
关键词：
摘要：
The author discusses a technique for fitting the logistic growth-function to data on mortality rates at various concs. of a drug. By a simple transformation (which is facilitated by a scale nomograph presented in the article) the function becomes linear. The usual least-squares soln. is then made and theoretical mortalities readily found. A numerical illustration is given. Using chi-square the results appear somewhat better than those obtained by use of the integral of the normal curve in 7 illustrations from the literature.