Approximate Selective Inference via Maximum Likelihood

• 成果类型: Article
• 署名作者: Panigrahi, Snigdha; Taylor, Jonathan
• 署名单位: University of Michigan System; University of Michigan; Stanford University
• 刊物名称: JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
• ISSN/ISSBN: 0162-1459
• DOI: 10.1080/01621459.2022.2081575
• 发表日期: 2023
• 页码: 2810-2820
• 关键词: model-selection; variable selection

摘要

Several strategies have been developed recently to ensure valid inference after model selection; some of these are easy to compute, while others fare better in terms of inferential power. In this article, we consider a selective inference framework for Gaussian data. We propose a new method for inference through approximate maximum likelihood estimation. Our goal is to: (a) achieve better inferential power with the aid of randomization, (b) bypass expensive MCMC sampling from exact conditional distributions that are hard to evaluate in closed forms. We construct approximate inference, for example, p-values, confidence intervals etc., by solving a fairly simple, convex optimization problem. We illustrate the potential of our method across wide-ranging values of signal-to-noise ratio in simulations. On a cancer gene expression dataset we find that our method improves upon the inferential power of some commonly used strategies for selective inference. Supplementary materials for this article are available online.