LOCALLY ASSOCIATED GRAPHICAL MODELS AND MIXED CONVEX EXPONENTIAL FAMILIES

成果类型:
Article
署名作者:
Lauritzen, Steffen; Zwiernik, Piotr
署名单位:
University of Copenhagen; University of Toronto
刊物名称:
ANNALS OF STATISTICS
ISSN/ISSBN:
0090-5364
DOI:
10.1214/22-AOS2219
发表日期:
2022
页码:
3009-3038
关键词:
maximum-likelihood-estimation marginal homogeneity total positivity INFORMATION variables selection geometry network
摘要:
The notion of multivariate total positivity has proved to be useful in finance and psychology but may be too restrictive in other applications. In this paper, we propose a concept of local association, where highly connected components in a graphical model are positively associated and study its properties. Our main motivation comes from gene expression data, where graphical models have become a popular exploratory tool. The models are instances of what we term mixed convex exponential families and we show that a mixed dual likelihood estimator has simple exact properties for such families as well as asymptotic properties similar to the maximum likelihood estimator. We further relax the positivity assumption by penalizing negative partial correlations in what we term the positive graphical lasso. Finally, we develop a GOLAZO algorithm based on block-coordinate descent that applies to a number of optimization procedures that arise in the context of graphical models, including the estimation problems described above. We derive results on existence of the optimum for such problems.