STOCHASTIC MODELS OF HOST-MACROPARASITE INTERACTION
成果类型:
Article
署名作者:
Isham, Valerie
署名单位:
University of London; University College London
刊物名称:
ANNALS OF APPLIED PROBABILITY
ISSN/ISSBN:
1050-5164
DOI:
10.1214/aoap/1177004702
发表日期:
1995
页码:
720-740
关键词:
摘要:
The interactions between macroparasites and their hosts, in terms of parasite-induced acquired immunity and additional mortality of the host, are of considerable interest and importance. In this paper, a simple nonlinear stochastic model for the parasite load within a single host over the lifetime of the host is investigated. By concentrating on a model incorporating only parasite-induced excess host mortality, exact algebraic results are possible, which provide insight into the effects of this interaction mechanism. A method of approximating the moments of parasite load is explored under a range of parametric assumptions. Extensions of the model to allow for heterogeneity between hosts and to incorporate various types of acquired immunity within the host are discussed briefly.
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