High- resolution stereolithography: Negative spaces enabled by control of fluid mechanics

• 成果类型: Article
• 署名作者: Coates, Ian A.; Pan, William; Saccone, Max A.; Lipkowitz, Gabriel; Ilyin, Dan; Driskill, Madison M.; Dulay, Maria T.; Frank, Curtis W.; Shaqfeh, Eric S. G.; Desimone, Joseph M.
• 署名单位: Stanford University; Stanford University; Stanford University
• 刊物名称: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• ISSN/ISSBN: 0027-12069
• DOI: 10.1073/pnas.2405382121
• 发表日期: 2024-09-10
• 关键词: microfluidics; networks

摘要

Stereolithography enables the fabrication of three- dimensional (3D) freeform structures via light- induced polymerization. However, the accumulation of ultraviolet dose within resin trapped in negative spaces, such as microfluidic channels or voids, can result in the unintended closing, referred to as overcuring, of these negative spaces. We report the use of injection continuous liquid interface production to continuously displace resin at risk of overcuring in negative spaces created in previous layers with fresh resin to mitigate the loss of Z- axis resolution. We demonstrate the ability to resolve 50-mu m microchannels, breaking the historical relationship between resin properties and negative space resolution. With this approach, we fabricated proof- of- concept 3D free- form microfluidic devices with improved design freedom over device material selection and