Maize resistance to witchweed through changes in strigolactone biosynthesis

• 成果类型: Article
• 署名作者: Li, C.; Dong, L.; Durairaj, J.; Guan, J. -C.; Yoshimura, M.; Quinodoz, P.; Horber, R.; Gaus, K.; Li, J.; Setotaw, Y. B.; Qi, J.; De Groote, H.; Wang, Y.; Thiombiano, B.; Flokova, K.; Walmsley, A.; Charnikhova, T. V.; Chojnacka, A.; de Lemos, S. Correia; Ding, Y.; Skibbe, D.; Hermann, K.; Screpanti, C.; De Mesmaeker, A.; Schmelz, E. A.; Menkir, A.; Medema, M.; Van Dijk, A. D. J.; Wu, J.; Koch, K. E.; Bouwmeester, H. J.
• 署名单位: University of Amsterdam; Wageningen University & Research; State University System of Florida; University of Florida; Swiss Federal Institutes of Technology Domain; ETH Zurich; Syngenta; Kyoto University; Chinese Academy of Sciences; Kunming Institute of Botany, CAS; CGIAR; International Maize & Wheat Improvement Center (CIMMYT); Czech Academy of Sciences; Institute of Experimental Botany of the Czech Academy of Sciences; Palacky University Olomouc; Universidade Estadual Paulista; University of California System; University of California San Diego; Syngenta; CGIAR; International Institute of Tropical Agriculture (IITA); University of Basel
• 刊物名称: SCIENCE
• ISSN/ISSBN: 0036-9714
• DOI: 10.1126/science.abq4775
• 发表日期: 2023-01-06
• 页码: 94-99
• 关键词: carlactonoic acid; germination; max1; architecture; arabidopsis; inhibition; cleavage; host

摘要

Maize (Zea mays) is a major staple crop in Africa, where its yield and the livelihood of millions are compromised by the parasitic witchweed Striga. Germination of Striga is induced by strigolactones exuded from maize roots into the rhizosphere. In a maize germplasm collection, we identified two strigolactones, zealactol and zealactonoic acid, which stimulate less Striga germination than the major maize strigolactone, zealactone. We then showed that a single cytochrome P450, ZmCYP706C37, catalyzes a series of oxidative steps in the maize-strigolactone biosynthetic pathway. Reduction in activity of this enzyme and two others involved in the pathway, ZmMAX1b and ZmCLAMT1, can change strigolactone composition and reduce Striga germination and infection. These results offer prospects for breeding Striga-resistant maize.