Comment on Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
成果类型:
Editorial Material
署名作者:
Herai, Roberto H.; Semendeferi, Katerina; Muotri, Alysson R.
署名单位:
Pontificia Universidade Catolica do Parana; University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego
刊物名称:
SCIENCE
ISSN/ISSBN:
0036-13932
DOI:
10.1126/science.adf0602
发表日期:
2023-03-10
页码:
379-+
关键词:
摘要:
Pinson et al. (1) concluded that the modern human TKTL1 gene is responsible for an increased number of cortical neurons. We show that the putative Neanderthal variant of TKTL1 is present in modern human backgrounds. We dispute their argument that this genetic variant is responsible for brain differences in modern humans as opposed to Neanderthals.