Brassinosteroid coordinates cell layer interactions in plants via cell wall and tissue mechanics

• 成果类型: Article
• 署名作者: Kelly-Bellow, Robert; Lee, Karen; Kennaway, Richard; Barclay, J. Elaine; Whibley, Annabel; Bushell, Claire; Spooner, Jamie; Yu, Man; Brett, Paul; Kular, Baldeep; Cheng, Shujing; Chu, Jinfang; Xu, Ting; Lane, Brendan; Fitzsimons, James; Xue, Yongbiao; Smith, Richard S.; Whitewoods, Christopher D.; Coen, Enrico
• 署名单位: UK Research & Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC); John Innes Center; UK Research & Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC); John Innes Center; Chinese Academy of Sciences; Institute of Genetics & Developmental Biology, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Chinese Academy of Sciences; Institute of Genetics & Developmental Biology, CAS; UK Research & Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC); John Innes Center; University of Cambridge
• 刊物名称: SCIENCE
• ISSN/ISSBN: 0036-13523
• DOI: 10.1126/science.adf0752
• 发表日期: 2023-06-01
• 页码: 1275-1281
• 关键词: arabidopsis-thaliana; herbaceous plants; gene-expression; GROWTH; elongation; hypocotyl; stresses; identification; drives; organs

摘要

Growth coordination between cell layers is essential for development of most multicellular organisms. Coordination may be mediated by molecular signaling and/or mechanical connectivity between cells, but how genes modify mechanical interactions between layers is unknown. Here we show that genes driving brassinosteroid synthesis promote growth of internal tissue, at least in part, by reducing mechanical epidermal constraint. We identified a brassinosteroid-deficient dwarf mutant in the aquatic plant Utricularia gibba with twisted internal tissue, likely caused by mechanical constraint from a slow-growing epidermis. We tested this hypothesis by showing that a brassinosteroid mutant in Arabidopsis enhances epidermal crack formation, indicative of increased tissue stress. We propose that by remodeling cell walls, brassinosteroids reduce epidermal constraint, showing how genes can control growth coordination between layers by means of mechanics.