Phylogenomic analyses provide insights into primate evolution

• 成果类型: Article
• 署名作者: Shao, Yong; Zhou, Long; Li, Fang; Zhao, Lan; Zhang, Bao-Lin; Shao, Feng; Chen, Jia-Wei; Chen, Chun-Yan; Bi, Xupeng; Zhuang, Xiao-Lin; Zhu, Hong-Liang; Hu, Jiang; Sun, Zongyi; Li, Xin; Wang, Depeng; Rivas-Gonzalez, Iker; Wang, Sheng; Wang, Yun-Mei; Chen, Wu; Li, Gang; Lu, Hui-Meng; Liu, Yang; Kuderna, Lukas F. K.; Farh, Kyle Kai-How; Fan, Peng-Fei; Yu, Li; Li, Ming; Liu, Zhi-Jin; Tiley, George P.; Yoder, Anne D.; Roos, Christian; Hayakawa, Takashi; Marques-Bonet, Tomas; Rogers, Jeffrey; Stenson, Peter D.; Cooper, David N.; Schierup, Mikkel Heide; Yao, Yong-Gang; Zhang, Ya-Ping; Wang, Wen; Qi, Xiao-Guang; Zhang, Guojie; Wu, Dong-Dong
• 署名单位: Chinese Academy of Sciences; Kunming Institute of Zoology, CAS; Zhejiang University; Zhejiang University; University of Copenhagen; Northwest University Xi'an; Southwest University - China; Beijing Genomics Institute (BGI); Northwestern Polytechnical University; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Aarhus University; Shaanxi Normal University; Northwestern Polytechnical University; Pompeu Fabra University; Barcelona Biomedical Research Park; Consejo Superior de Investigaciones Cientificas (CSIC); CSIC-UPF - Institut de Biologia Evolutiva (IBE); Illumina; Sun Yat Sen University; Yunnan University; Chinese Academy of Sciences; Institute of Zoology, CAS; Capital Normal University; Duke University; Leibniz Association; Deutsches Primatenzentrum (DPZ); Hokkaido University; Kyoto University; ICREA; Baylor College of Medicine; Cardiff University; Chinese Academy of Sciences; Kunming Institute of Zoology, CAS; Chinese Academy of Sciences; Chinese Academy of Sciences; Kunming Institute of Zoology, CAS; Chinese Academy of Sciences; Kunming Institute of Zoology, CAS; Zhejiang University; Liangzhu Laboratory; Chinese Academy of Sciences; Kunming Institute of Zoology, CAS; Barcelona Institute of Science & Technology; Pompeu Fabra University; Centre de Regulacio Genomica (CRG); Autonomous University of Barcelona; Institut Catala de Paleontologia Miquel Crusafont (ICP)
• 刊物名称: SCIENCE
• ISSN/ISSBN: 0036-9465
• DOI: 10.1126/science.abn6919
• 发表日期: 2023-06-02
• 页码: 913-924
• 关键词: discs large 5; organ size; molecular clock; messenger-rna; axon guidance; citron kinase; brain-size; genome; expression; mechanisms

摘要

Comparative analysis of primate genomes within a phylogenetic context is essential for understanding the evolution of human genetic architecture and primate diversity. We present such a study of 50 primate species spanning 38 genera and 14 families, including 27 genomes first reported here, with many from previously less well represented groups, the New World monkeys and the Strepsirrhini. Our analyses reveal heterogeneous rates of genomic rearrangement and gene evolution across primate lineages. Thousands of genes under positive selection in different lineages play roles in the nervous, skeletal, and digestive systems and may have contributed to primate innovations and adaptations. Our study reveals that many key genomic innovations occurred in the Simiiformes ancestral node and may have had an impact on the adaptive radiation of the Simiiformes and human evolution.