Cross-modal representation of identity in the primate hippocampus

• 成果类型: Article
• 署名作者: Tyree, Timothy J.; Metke, Michael; Miller, Cory T.
• 署名单位: University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego
• 刊物名称: SCIENCE
• ISSN/ISSBN: 0036-13686
• DOI: 10.1126/science.adf0460
• 发表日期: 2023-10-27
• 页码: 417-423
• 关键词: single neurons; face identity; responses; memory; cells; RECOGNITION; selectivity

摘要

Faces and voices are the dominant social signals used to recognize individuals among primates. Yet, it is not known how these signals are integrated into a cross-modal representation of individual identity in the primate brain. We discovered that, although single neurons in the marmoset hippocampus exhibited selective responses when presented with the face or voice of a specific individual, a parallel mechanism for representing the cross-modal identities for multiple individuals was evident within single neurons and at the population level. Manifold projections likewise showed the separability of individuals as well as clustering for others' families, which suggests that multiple learned social categories are encoded as related dimensions of identity in the hippocampus. Neural representations of identity in the hippocampus are thus both modality independent and reflect the primate social network.