Cascade-heterogated biphasic gel iontronics for electronic-to-multi-ionic signal transmission

• 成果类型: Article
• 署名作者: Chen, Weipeng; Zhai, Linxin; Zhang, Suli; Zhao, Ziguang; Hu, Yuhao; Xiang, Yun; Liu, Huirong; Xu, Zhiping; Jiang, Lei; Wen, Liping
• 署名单位: Chinese Academy of Sciences; Technical Institute of Physics & Chemistry, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Tsinghua University; Capital Medical University; Capital Medical University
• 刊物名称: SCIENCE
• ISSN/ISSBN: 0036-10444
• DOI: 10.1126/science.adg0059
• 发表日期: 2023-11-03
• 页码: 559-565
• 关键词: synapse

摘要

Currently, electronics and iontronics in abiotic-biotic systems can only use electrons and single-species ions as unitary signal carriers. Thus, a mechanism of gating transmission for multiple biosignals in such devices is needed to match and modulate complex aqueous-phase biological systems. Here we report the use of cascade-heterogated biphasic gel iontronics to achieve diverse electronic-to-multi-ionic signal transmission. The cascade-heterogated property determined the transfer free energy barriers experienced by ions and ionic hydration-dehydration states under an electric potential field, fundamentally enhancing the distinction of cross-interface transmission between different ions by several orders of magnitude. Such heterogated or chemical-heterogated iontronics with programmable features can be coupled with multi-ion cross-interface mobilities for hierarchical and selective cross-stage signal transmission. We expect that such iontronics would be ideal candidates for a variety of biotechnology applications.