The genetic basis of a recent transition to live-bearing in marine snails

• 成果类型: Article
• 署名作者: Stankowski, Sean; Zagrodzka, Zuzanna B.; Garlovsky, Martin D.; Pal, Arka; Shipilina, Daria; Castillo, Diego Garcia; Lifchitz, Hila; Le Moan, Alan; Leder, Erica; Reeve, James; Johannesson, Kerstin; Westram, Anja M.; Butlin, Roger K.
• 署名单位: University of Sheffield; Institute of Science & Technology - Austria; University of Sussex; Technische Universitat Dresden; Uppsala University; Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; University of Gothenburg; University of Oslo; Nord University
• 刊物名称: SCIENCE
• ISSN/ISSBN: 0036-8185
• DOI: 10.1126/science.adi2982
• 发表日期: 2024-01-05
• 页码: 114-119
• 关键词: phylogenetic analysis; local adaptation; key innovation; r-package; EVOLUTION; littorina; format; trees; face

摘要

Key innovations are fundamental to biological diversification, but their genetic basis is poorly understood. A recent transition from egg-laying to live-bearing in marine snails (Littorina spp.) provides the opportunity to study the genetic architecture of an innovation that has evolved repeatedly across animals. Individuals do not cluster by reproductive mode in a genome-wide phylogeny, but local genealogical analysis revealed numerous small genomic regions where all live-bearers carry the same core haplotype. Candidate regions show evidence for live-bearer-specific positive selection and are enriched for genes that are differentially expressed between egg-laying and live-bearing reproductive systems. Ages of selective sweeps suggest that live-bearer-specific alleles accumulated over more than 200,000 generations. Our results suggest that new functions evolve through the recruitment of many alleles rather than in a single evolutionary step.