Tactile edges and motion via patterned microstimulation of the human somatosensory cortex

• 成果类型: Article
• 署名作者: Valle, Giacomo; Alamri, Ali H.; Downey, John E.; Lienkamper, Robin; Jordan, Patrick M.; Sobinov, Anton R.; Endsley, Linnea J.; Prasad, Dillan; Boninger, Michael L.; Collinger, Jennifer L.; Warnke, Peter C.; Hatsopoulos, Nicholas G.; Miller, Lee E.; Gaunt, Robert A.; Greenspon, Charles M.; Bensmaia, Sliman J.
• 署名单位: University of Chicago; Chalmers University of Technology; University of Chicago; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; University of Chicago; University of Chicago; Northwestern University; Northwestern University; Northwestern University
• 刊物名称: SCIENCE
• ISSN/ISSBN: 0036-8920
• DOI: 10.1126/science.adq5978
• 发表日期: 2025-01-17
• 页码: 315-322
• 关键词: shape perception; stimulation; mechanisms; signals; integration; sensations; CURVATURE; illusion; vision

摘要

Intracortical microstimulation (ICMS) of somatosensory cortex evokes tactile sensations whose properties can be systematically manipulated by varying stimulation parameters. However, ICMS currently provides an imperfect sense of touch, limiting manual dexterity and tactile experience. Leveraging our understanding of how tactile features are encoded in the primary somatosensory cortex (S1), we sought to inform individuals with paralysis about local geometry and apparent motion of objects on their skin. We simultaneously delivered ICMS through electrodes with spatially patterned projected fields (PFs), evoking sensations of edges. We then created complex PFs that encode arbitrary tactile shapes and skin indentation patterns. By delivering spatiotemporally patterned ICMS, we evoked sensation of motion across the skin, the speed and direction of which could be controlled. Thus, we improved individuals' tactile experience and use of brain-controlled bionic hands.