Pharmaceutical pollution influences river-to-sea migration in Atlantic salmon (Salmo salar)

• 成果类型: Article
• 署名作者: Brand, Jack A.; Michelangeli, Marcus; Shry, Samuel J.; Moore, Eleanor R.; Bose, Aneesh P. H.; Cerveny, Daniel; Martin, Jake M.; Hellstroem, Gustav; McCallum, Erin S.; Holmgren, Annika; Thore, Eli S. J.; Fick, Jerker; Brodin, Tomas; Bertram, Michael G.
• 署名单位: Swedish University of Agricultural Sciences; Zoological Society of London; Griffith University; Monash University; Karlstad University; Max Planck Society; University of South Bohemia Ceske Budejovice; Deakin University; Stockholm University; University of Namur; KU Leuven; Umea University
• 刊物名称: SCIENCE
• ISSN/ISSBN: 0036-10116
• DOI: 10.1126/science.adp7174
• 发表日期: 2025-04-10
• 页码: 217-222
• 关键词: waste-water treatment; BEHAVIOR; survival; smolts; fish; contaminants; environment; trutta

摘要

Despite the growing threat of pharmaceutical pollution, we lack an understanding of whether and how such pollutants influence animal behavior in the wild. Using laboratory- and field-based experiments across multiple years in Atlantic salmon (Salmo salar; n = 730), we show that the globally detected anxiolytic pollutant clobazam accumulates in the brain of exposed fish and influences river-to-sea migration success. Clobazam exposure increased the speed with which fish passed through two hydropower dams along their migration route, resulting in more clobazam-exposed fish reaching the sea compared with controls. We argue that such effects may arise from altered shoaling behavior in fish exposed to clobazam. Drug-induced behavioral changes are expected to have wide-ranging consequences for the ecology and evolution of wild populations.