Drop-printing with dynamic stress release for conformal wrap of bioelectronic interfaces

• 成果类型: Article
• 署名作者: Li, An; Zhou, Wenjianlong; Li, Huizeng; Fang, Wei; Luo, Yifei; Li, Zheng; Zhang, Qingrong; Liu, Quan; Xu, Qin; Xue, Luanluan; Li, Kaixuan; Yuan, Renxuan; Liu, Wanling; Jia, Wang; Chen, Xiaodong; Song, Yanlin
• 署名单位: Chinese Academy of Sciences; Institute of Chemistry, CAS; Capital Medical University; Tianjin University; Agency for Science Technology & Research (A*STAR); A*STAR - Institute of Materials Research & Engineering (IMRE); Army Medical University; Army Medical University; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Nanyang Technological University
• 刊物名称: SCIENCE
• ISSN/ISSBN: 0036-13165
• DOI: 10.1126/science.adw6854
• 发表日期: 2025-09-11
• 页码: 1127-1132
• 关键词: thin-films; electronics; IMPACT

摘要

Bioelectronic interfaces demonstrate promising applications in health monitoring, medical treatment, and augmented reality. However, conformally wrapping these film devices onto three-dimensional surfaces often leads to stress-induced damage. We propose a drop-printing strategy that enables damage-free film transfer using a droplet. The droplet acts as a lubricating layer between the film and the target surface, facilitating local sliding during shape-adaptive deformation. This mechanism prevents in-plane film stretching and reduces stress concentration. Even nonstretchable and fragile films can be intactly and accurately wrapped onto delicate surfaces, such as microscale microorganisms and optical fibers. Two-micrometer-thick silicon films, without any stretchable engineering, can form conformal neural-electronic interfaces by being drop-printed on nerves and brain tissue. The interfaces achieve light-controlled in vivo neuromodulation with high spatiotemporal resolution.