Tumours form without genetic mutations

• 成果类型: Editorial Material
• 署名作者: Classen, Anne-Kathrin
• 署名单位: University of Freiburg; University of Freiburg
• 刊物名称: Nature
• ISSN/ISSBN: 0028-6490
• DOI: 10.1038/d41586-024-01019-2
• 发表日期: 2024-05-16
• 页码: 534-535
• 关键词: suppressor activity; cancer; jak/stat

摘要

Researchers find that brief and reversible inhibition of a gene-silencing mechanism leads to irreversible tumour formation in fruit flies, challenging the idea that cancer is caused only by permanent changes to DNA.