Global sites for mutations of unknown origins

• 成果类型: Editorial Material
• 署名作者: Franco, Irene; Supek, Fran
• 署名单位: Vita-Salute San Raffaele University; Vita-Salute San Raffaele University; IRCCS Ospedale San Raffaele; University of Copenhagen; Barcelona Institute of Science & Technology; Institute for Research in Biomedicine - IRB Barcelona
• 刊物名称: Nature
• ISSN/ISSBN: 0028-5696
• DOI: 10.1038/d41586-024-01190-6
• 发表日期: 2024-05-23
• 页码: 767-768
• 关键词: signatures; landscape

摘要

Genetic sequencing of human kidney cancers worldwide has revealed associations between geographical locations and specific mutation patterns, indicating exposure to known and unknown mutation-promoting agents.