Cells cope with altered chromosome numbers by enhancing protein breakdown

• 成果类型: News Item
• 署名作者: Storchova, Zuzana
• 刊物名称: Nature
• ISSN/ISSBN: 0028-6484
• DOI: 10.1038/d41586-024-01360-6
• 发表日期: 2024-06-06
• 页码: 41-43
• 关键词: aneuploidy; reveals

摘要

When chromosomes are lost or gained, massive changes in gene expression disrupt the delicate balance of proteins in a cell. Yeasts with incorrect chromosome numbers counteract this by degrading excess proteins.