The liver converts fructose into lipids to fuel tumours

• 成果类型: Editorial Material
• 署名作者: Medeiros, Hyllana C. D.; Lunt, Sophia Y.
• 署名单位: Michigan State University; Michigan State University
• 刊物名称: Nature
• ISSN/ISSBN: 0028-5103
• DOI: 10.1038/d41586-024-03653-2
• 发表日期: 2024-12-19
• 页码: 580-581
• 关键词: serine

摘要

Fructose aids tumour growth, but cancer cells usually lack the enzymes needed to metabolize this sugar. The liver converts dietary fructose to lipids that enter the blood, and cancer cells use the lipids to make membranes for proliferation.